View abstract. View abstract. From diagnosis to treatment, our experts provide the care and support you need, when you need it. Used alone, it can make the formula sticky and it is a good team player so it is usually combined with other thickeners and so-called rheology modifiers (helper ingredients that adjust the flow and thus the feel Use of this Web site does not create an expressed or implied physician-patient relationship. Suppressive effect of wogonin on mite antigen-induced TARC expression. View abstract. You are hereby advised to consult with a physician or other professional health-care provider prior to making any decisions, or undertaking any actions or not undertaking any actions related to any health care problem or issue you might have at any time, now or in the future. Lee, E., Enomoto, R., Suzuki, C., Ohno, M., Ohashi, T., Miyauchi, A., Tanimoto, E., Maeda, K., Hirano, H., Yokoi, T., and Sugahara, C. Wogonin, a plant flavone, potentiates etoposide-induced apoptosis in cancer cells. This study reports three major findings: (1) S. baicalensis has a potent inhibitory effect Chou TC, Chang LP, Li CY, et al. Gabrielska, J., Oszmianski, J., Zylka, R., and Komorowska, M. Antioxidant activity of flavones from Scutellaria baicalensis in lecithin liposomes. Liao, H. L. and Hu, M. K. Synthesis and anticancer activities of 5,6,7-trimethylbaicalein derivatives. Ye, F., Xui, L., Yi, J., Zhang, W., and Zhang, D. Y. Anticancer activity of Scutellaria baicalensis and its potential mechanism. View abstract. Kang, T. H., Hong, B. N., Park, C., Kim, S. Y., and Park, R. Effect of baicalein from Scutellaria baicalensis on prevention of noise-induced hearing loss. View abstract. Armstrong, T. S. and Gilbert, M. R. Use of complementary and alternative medical therapy by patients with primary brain tumors. Jeong, K., Shin, Y. C., Park, S., Park, J. S., Kim, N., Um, J. Y., Go, H., Sun, S., Lee, S., Park, W., Choi, Y., Song, Y., Kim, G., Jeon, C., Park, J., Lee, K., Bang, O., and Ko, S. G. Ethanol extract of Scutellaria baicalensis Georgi prevents oxidative damage and neuroinflammation and memorial impairments in artificial senescense mice. Some medications are changed and broken down by the liver. Li, T., Li, N., Guo, Q., Ji, H., Zhao, D., Xie, S., Li, X., Qiu, Z., Han, D., Chen, X., and You, Q. Inhibitory effects of wogonin on catalytic activity of cytochrome P450 enzyme in human liver microsomes. Zhou, J., Qu, F., Zhang, H. J., Zhuge, X. H., and Cheng, L. Z. Biological properties of baicalein in cardiovascular system. View abstract. People with diabetes should not take Chinese skullcap without consulting a doctor as it may lower blood sugar, increasing the risk of hypoglycemia. There have been reports of fever and lung inflammation in people who took Baikal skullcap. The flavonoid baicalin exhibits anti-inflammatory activity by binding to chemokines. J Ethnopharmacol. Ann Intern Med 2012;156:894-5. A combination of Scutellaria baicalensis and Acacia catechu for short-term symptomatic relief of joint discomfort associated with osteoarthritis of the knee. Opposite expression of securin and gamma-H2AX regulates baicalein-induced cancer cell death. View abstract. Morgan SL, Baggott JE, Moreland L, et al. View abstract. Avoid skin and eye contact and breathing in dust. View abstract. Preclinical studies of S. barbata have focused mostly on colon, lung, and liver cancer models. Analysis of essential oils from different organs of Scutellaria baicalensis. Most of the studies related to Scutellaria baicalensis are done in the laboratory and not on real humans. [The Baikal scullcap (Scutellaria baicalensis Georgi)--a potential source of new drugs]. Invest New Drugs 2011;29(4):637-645. Yang, L., Zheng, X. L., Sun, H., Zhong, Y. J., Wang, Q., He, H. N., Shi, X. W., Zhou, B., Li, J. K., Lin, Y., Zhang, L., and Wang, X. Catalase suppression-mediated H(2)O(2) accumulation in cancer cells by wogonin effectively blocks tumor necrosis factor-induced NF-kappaB activation and sensitizes apoptosis. 7-28-2004;211(1):39-46. 1989;35(3):331-335. Konoshima, T., Kokumai, M., Kozuka, M., Iinuma, M., Mizuno, M., Tanaka, T., Tokuda, H., Nishino, H., and Iwashima, A. Pharmacol Res 2001;43(2):173-178. Toxicology 5-2-2009;259(1-2):10-17. Zhou, X. Q., Liang, H., Lu, X. H., Cai, S. Q., Wang, B., and Zhao, Y. Y. 2004;91(1):65-68. 2009;110(4):1276-1287. Am J Chin Med 2001;29(1):69-81. View abstract. View abstract. International Journal of Pharmacology 2010;6(2):81-88. Macrophages are specifically involved in the initiation, maintenance, and resolution of inflammation. Health-related information changes frequently and therefore information contained on this Web site may be outdated, incomplete or incorrect. View abstract. Treatment of acute bronchiolitis with Chinese herbs. Biol Pharm Bull 2004;27(10):1580-1583. Ready to start planning your care? With cancer, where you get treated first matters. View abstract. Keep in mind that natural products are not always necessarily safe and dosages can be important. View abstract. XI. Cancer Sci 2011;102(4):870-876. 2010;16(2):32-40. This side effect does not appear to be common and might only occur in people who have a type of allergic reaction to it. Whether co-administration of garlic has negative influence on Scutellaria baicalensis Georgi in treating models rats with pelvic inflammation? A traditional Chalasani N, Vuppalanchi R, Navarro V, et al. Different extracts of this herb have been found to kill cancer cells in the body, but human research is pending in this field. Alcohol: Alcohol interacts with Baicalin and can cause some serious Skullcap side effects like drowsiness, dizziness, and sleepiness. The pharmacology of Chinese herbs. Mol Pharmacol 2001;60(3):507-513. Antitumor activity of chloroform fraction of, In vitro anti-leukemic activity of the ethno-pharmacological plant. Linnebur, S. A., Rapacchietta, O. C., and Vejar, M. Hepatotoxicity associated with chinese skullcap contained in Move Free Advanced dietary supplement: two case reports and review of the literature. J Med Chem 10-21-2004;47(22):5555-5566. 5-17-2011;135(2):359-368. Induction of apoptosis in prostate cancer cell lines by a flavonoid, baicalin. Zhou J, Qu F, Yu Y, et al. View abstract. 2010;17(1):47-54. Z., Bai, L., Chen, D. G., Xu, Q. T., and Southerland, W. M. Computational investigation of the anti-HIV activity of Chinese medicinal formula Three-Huang Powder. Planta Med 2000;66:70-1. View abstract. You are hereby advised to consult with a physician or other professional health-care provider prior to making any decisions, or undertaking any actions or not undertaking any actions related to any health care problem or issue you might have at any time, now or in the future. View abstract. 5-24-2006;105(3):346-351. Biomed Res Int 2016;2016:5697571. But there is not enough information to know if Baikal skullcap is the cause of these side effects. No matter new buyer or old purchaser, We believe in long expression and trusted relationship for Scutellaria Baicalensis Root, Nootropics Modafinil, Herbal Extract Oil, Maca Extract Liquid, Hawthorn Extract Vs Hawthorn Berry. View abstract. However Baikal skullcap is not as strong as estrogen pills. Huang, R. L., Chen, C. C., Huang, H. L., Chang, C. G., Chen, C. F., Chang, C., and Hsieh, M. T. Anti-hepatitis B virus effects of wogonin isolated from Scutellaria baicalensis. Acta Pharmacol Sin. Int Immunopharmacol. Zhang H and Huang J. 2009;29(5):1286-1288. Fan L, Zhang W, Guo D, et al. Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings). Anticonvulsant effect of wogonin isolated from. J Med Food 2007;10:442-51. Baikal skullcap might cause sleepiness and drowsiness. View abstract. Krakauer, T., Li, B. Q., and Young, H. A. Hu, J. Clin Cancer Res 5-15-2005;11(10):3905-3914. You, J., Gao, S., Jin, H., Li, W., Zhang, H., and Yu, A. On-line continuous flow ultrasonic extraction coupled with high performance liquid chromatographic separation for determination of the flavonoids from root of Scutellaria baicalensis Georgi. J Hazard.Mater. In theory, Baikal skullcap might increase the risk of bruising and bleeding in people with bleeding disorders. Wu X, Zhang H, Salmani JM, et al. View abstract. J Agric Food Chem 12-3-2003;51(25):7276-7279. Cheng, K. T., Hou, W. C., Huang, Y. C., and Wang, L. F. Baicalin induces differential expression of cytochrome C oxidase in human lung H441 cell. View abstract. View abstract. Zhang, X. W., Li, W. F., Li, W. W., Ren, K. H., Fan, C. M., Chen, Y. Y., and Shen, Y. L. Protective effects of the aqueous extract of Scutellaria baicalensis against acrolein-induced oxidative stress in cultured human umbilical vein endothelial cells. Br J Pharmacol 2009;157:1410-18. View abstract. 1998;61(2):54-56. View abstract. [14] However, both S. baicalensis root and its main flavonoid baicalin appear to have dose-dependent pro- and anti-angiogenic effects . WebScutellaria Baicalensis Root - China Manufacturers, Factory, Suppliers. Total flavonoids induced increases in DNA fragmentation and mitochondrial pathway apoptosis(30). In vitro studies suggest that S. barbata has antibacterial(1), antioxidant(15), antimutagenic(2), and anticancer(3)(4)(5)(6)(7)(8)(10)(11)(12) properties. New York, NY: CRC Press LLC. Most studies have been done in the lab rather than in humans, and suggest anti-inflammatory and antioxidant activity. There have been several reports and small case series of acute liver injury with jaundice arising after 1 to 3 months of starting herbals or dietary supplements with View abstract. Liao JF, Wang HH, Chen MC, et al. 1997;57(1):63-67. Hong, T., Jeong, M. L., Zahn, M., Fay, B. In some cases, this might change the effects and side effects of a medication. Get medical attention if irritation develops and persists. J Biomed.Sci 2009;16:27. View abstract. There are a number of different names that people use for Baicalin. View abstract. Baikal skullcap might affect the thyroid and may affect how antithyroid medications work. Yoon, S. B., Lee, Y. J., Park, S. K., Kim, H. C., Bae, H., Kim, H. M., Ko, S. G., Choi, H. Y., Oh, M. S., and Park, W. Anti-inflammatory effects of Scutellaria baicalensis water extract on LPS-activated RAW 264.7 macrophages. Watch for signs of low blood sugar (hypoglycemia) and monitor your blood sugar carefully if you have diabetes and use Baikal skullcap. Chemicals in skullcap might cause sleepiness. B., Ro, J. Y., and Woo, S. S. Antiallergic herbal composition from Scutellaria baicalensis and Phyllostachys edulis. View abstract. Li BQ, Fu T, Gong WH, et al. Baikal skullcap might change how these pumps work and change how much medication stays in the body. View abstract. Some of these sedative medications include clonazepam (Klonopin), diazepam (Valium), lorazepam (Ativan), and others. 1997;11(3):125-131. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. 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